Media release from Asthma AucklandFriday 29 June 2012, 1:58PM
Media release from Asthma Auckland
The results of a childhood asthma trial conducted in New Zealand
point to a popular Kiwi seafood extract improving the quality of
life for young people with asthma.
Asthma is one of the most common chronic diseases affecting young
children and adults in New Zealand, particularly during winter. But
a random, double-blind trial in children with moderate-severe
chronic obstructive asthma indicates the NZ green-lipped mussel's
lipid fatty acids can reduce the severity of asthma symptoms.
The clinical trial conducted by Asthma Auckland for Asthma New
Zealand and the results have just been published in the Journal of
Asthma, Allergy and Immunology.
They show that in capsule form Lyprinol, a safe natural supplement
which contains anti-oxidants and anti-inflammatory compounds,
widely used for the treatment of arthritis, can now be used by
children in conjunction with traditional steroid-based inhalers to
reduce the severity of symptoms and limit exacerbations. The
patented oil extract from the shellfish Perna canaliculus used in
Lyprinol, is sold in Australia, New Zealand and more than 28
countries around the world.
While further research is required, the study of 74 children aged
6-13, concluded that while the supplementation of this unique free
fatty acid combination did not reduce the amount of medication the
children were taking, "there were trends noted to improved quality
of life (Juniper Scale Measure) and a decreased rate of moderate
asthma exacerbations in those children randomised to the active
Study leader Dr J M Lello, an Auckland GP and Medical Adviser to
Asthma Auckland, says it was an encouraging result. "This is the
first time we have had information on the use of Lyprinol in
children with moderate to severe asthma.
"Although the primary outcome of steroid sparing was not
demonstrated, several secondary outcome measures (e.g. quality of
life measures and reduction in exacerbations) showed trends
suggesting benefits in this group of children with troublesome
The Juniper Scale Measure was filled out by the children's parents
and was developed to measure three functional challenges (physical,
emotional and social) that are most troublesome to children living
Dr Lello says the children with food allergies could safely take
the oil extract which was found to be devoid of allergens
associated with shellfish protein.
While recruitment of children for the study proved a challenge
across the greater Auckland area, 80 youngsters began the 4-month
trial and 72 completed the study.
JOURNAL OF ASTHMA, ALLERGY AND IMMUNOLOGY