For older people and frail people, the long-term benefit of medicines reduces and the potential for harm from adverse effects increases. When the benefit–risk balance changes in this way, medicine review and optimisation are important to simplify the therapeutic regimen, reduce inappropriate medicines and minimise risks. In this article, pharmacist prescriber Linda Bryant uses two case studies to illustrate important considerations during medicine reviews
Heart failure: Optimised use of new drugs offers solutions to old problems
Heart failure: Optimised use of new drugs offers solutions to old problems

Professor Ngaire Kerse says new medicines for heart failure have appeared in recent years. With optimised use, these support the main goal of treatment, which is periods of stability with good quality of life (ask your patients what that means for them)
Kia ora and welcome to New Zealand Doctor Rata Aotearoa
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1. Betty B, Fisher R. Optimising heart failure management: What GPs need to know. Goodfellow Symposium, 28 March 2021. goodfellowunit.org
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4. Atherton JJ, Sindone A, De Pasquale CG, et al. National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Guidelines for the prevention, detection, and management of heart failure in Australia 2018. Heart Lung Circ 2018;27(10):1123–208.