‘Undercover chlamydia’: Inquiries confirm no naughty deeds under the covers

In print

‘Undercover chlamydia’: Inquiries confirm no naughty deeds under the covers

By Massimo Giola
Undercover detective
No need to go undercover to expose an extramarital affair, many chlamydia “reinfections” are due to endogenous recolonisation [Image: Devin Kaselnak on Unsplash]

We welcome back infectious disease and sexual health specialist Massimo Giola as a regular contributor in 2022. Starting with chlamydia, each article in this series will cover one topic of interest, present a clinical case and explain the rationale for some of the recommendations in the new Aotearoa New Zealand STI Management Guidelines for use in primary care

Key points, There is growing evidence that sexually transmitted Chlamydia trachomatis establishes a persistent rectal reservoir that is refractory to treatment wi, Pract Green w Pale Yellow

Further reading:

  • Khosropour CM, Dombrowski JC, Vojtech L, et al. Rectal Chlamydia trachomatis infection: A narrative review of the state of the science and research priorities. Sex Transm Dis 2021;48(12):e223–27.
  • Rank RG, Yeruva L. Hidden in plain sight: chlamydial gastrointestinal infection and its relevance to persistence in human genital infection. Infect Immun 2014;82(4):1362–71.
  • Kong FY, Tabrizi SN, Fairley CK, et al. The efficacy of azithromycin and doxycycline for the treatment of rectal chlamydia infection: a systematic review and meta-analysis. J Antimicrob Chemother 2015;70(5):1290–97.
  • Chandra NL, Broad C, Folkard K, et al. Detection of Chlamydia trachomatis in rectal specimens in women and its association with anal intercourse: a systematic review and meta-analysis. Sex Transm Infect 2018;94(5):320–26.