Goodfellow Gems #56

Goodfellow Gems #56

Bruce Arroll

Bruce Arroll

goodfellow gem

Spironolactone; effective but regular serum potassium checks recommended forever

Spironolactone is effective for NYHA class III and IV heart failure and hypertension (4th or 5th line) but can be a difficult drug to use. Elevated
References

1.    KMC Verhamme et al. Spironolactone and risk of upper gastrointestinal events: population based case-control study BMJ 2006.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1539051/
2.    Spironolactone—potion or poison? Drug and Therapeutics Bulletin Feb 2017. http://dtb.bmj.com/content/55/2/13