For older people and frail people, the long-term benefit of medicines reduces and the potential for harm from adverse effects increases. When the benefit–risk balance changes in this way, medicine review and optimisation are important to simplify the therapeutic regimen, reduce inappropriate medicines and minimise risks. In this article, pharmacist prescriber Linda Bryant uses two case studies to illustrate important considerations during medicine reviews
No new cases of COVID-19
No new cases of COVID-19

Today there are no new cases of COVID-19 to report.
It has now been 85 days since the last case of COVID-19 was acquired locally from an unknown source.
There is no one in New Zealand receiving hospital-level care for COVID-19.
The total number of confirmed cases of COVID-19 remains at 1206, which is the number we report to the World Health Organization.
Yesterday our laboratories completed 2,307 tests.
That brings the total number of tests completed to date to 453,923
Testing remains an important part of our overall strategy to detect any community cases of COVID-19 as quickly as possible.
We all have a part to play and we’re encouraging anyone who is offered a swab, to take up that offer.