For older people and frail people, the long-term benefit of medicines reduces and the potential for harm from adverse effects increases. When the benefit–risk balance changes in this way, medicine review and optimisation are important to simplify the therapeutic regimen, reduce inappropriate medicines and minimise risks. In this article, pharmacist prescriber Linda Bryant uses two case studies to illustrate important considerations during medicine reviews
Atrial fibrillation and anticoagulation risk in advanced age a conundrum
Atrial fibrillation and anticoagulation risk in advanced age a conundrum

The risk–benefit assessment for anticoagulation in atrial fibrillation in the elderly is a conundrum, but considering the relative consequences of stroke, which might be greater than those of anticoagulant-related bleeds, can be of help in decision-making
Kia ora and welcome to New Zealand Doctor Rata Aotearoa
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