For older people and frail people, the long-term benefit of medicines reduces and the potential for harm from adverse effects increases. When the benefit–risk balance changes in this way, medicine review and optimisation are important to simplify the therapeutic regimen, reduce inappropriate medicines and minimise risks. In this article, pharmacist prescriber Linda Bryant uses two case studies to illustrate important considerations during medicine reviews
Paraproteins, monoclonal bands – are these immunoglobulin results significant?
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PRACTICE
Paraproteins, monoclonal bands – are these immunoglobulin results significant?
Wednesday 12 September 2018, 01:00 AM

Electrophoretogram trace within capillary electrophoresis software showing a result of a 5.6g/L paraprotein at the gamma region (pink peak)
FROM THE LAB
Monoclonal gammopathy of undetermined significance – MGUS – is a common premalignant condition in the over-50s’ population. This article discusses the many possible implications of this often-incidental finding
Key points
Monoclonal gammopathy of undetermined significance is a premalignant clonal plasma cell or lymphoplasmacytic disorder.
The maj
Kia ora and welcome to New Zealand Doctor Rata Aotearoa
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