For older people and frail people, the long-term benefit of medicines reduces and the potential for harm from adverse effects increases. When the benefit–risk balance changes in this way, medicine review and optimisation are important to simplify the therapeutic regimen, reduce inappropriate medicines and minimise risks. In this article, pharmacist prescriber Linda Bryant uses two case studies to illustrate important considerations during medicine reviews
Rules for life: Mind has no delete button and is not to be trusted
Rules for life: Mind has no delete button and is not to be trusted

Specialist GP Bruce Arroll looks at how the human mind contributes to emotional pain and distress. Understanding these processes leads to several helpful coping strategies
Kia ora and welcome to New Zealand Doctor Rata Aotearoa
Not a subscriber? Unlock this article by subscribing here.
1. Törneke N. Learning RFT: An introduction to relational frame theory and its clinical application. Oakland, CA: New Harbinger Publications; 2010.
2. Arroll B, Frischtak H, Roskvist R, et al. FACT effectiveness in primary care; a single visit RCT for depressive symptoms. Int J Psychiatry Med 2022;57(2):91–102.
3. Henwood S, Arroll B. Does polyvagal theory have any application in general practice? New Zealand Doctor, 14 September 2022.