For older people and frail people, the long-term benefit of medicines reduces and the potential for harm from adverse effects increases. When the benefit–risk balance changes in this way, medicine review and optimisation are important to simplify the therapeutic regimen, reduce inappropriate medicines and minimise risks. In this article, pharmacist prescriber Linda Bryant uses two case studies to illustrate important considerations during medicine reviews
Uterine fibroids: Patient-centred management starts with GPs
Uterine fibroids: Patient-centred management starts with GPs

This article reviews the diagnosis and treatment of uterine fibroids
Kia ora and welcome to New Zealand Doctor Rata Aotearoa
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1. Stewart EA, Laughlin-Tommaso SK, Catherino WH, et al. Uterine fibroids. Nat Rev Dis Primers 2016;2:16043.
2. Munro MG, Critchley HO, Broder MS, Fraser IS. FIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age. Int J Gynaecol Obstet 2011;113(1):3–13.
3. Glaser LM, Friedman J, Tsai S, et al. Laparoscopic myomectomy and morcellation: A review of techniques, outcomes, and practice guidelines. Best Pract Res Clin Obstet Gynaecol 2018;46:99–112.
4. Kroon B, Johnson N, Chapman M, et al. Fibroids in infertility--consensus statement from ACCEPT (Australasian CREI Consensus Expert Panel on Trial evidence). Aust N Z J Obstet Gynaecol 2011;51(4):289–95.
5. Metwally M, Raybould G, Cheong YC, Horne AW. Surgical treatment of fibroids for subfertility. Cochrane Database Syst Rev 2020;1(1):CD003857.
Further information: Wynn-Williams M. Uterine fibroids; from effects on fertility to the peri-menopause and beyond. Goodfellow Unit webinar. 19 October 2021.