Media echo-chamber amplifies ‘nocebo’ effect with drug brand switches: study

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Media echo-chamber amplifies ‘nocebo’ effect with drug brand switches: study

Newspaper reader
In 2018, news stories raised patient’s concerns Pharmac’s funding switch from branded drug Effexor to generic Enlafax caused symptoms like suicidal thoughts, nausea, fatigue, headaches and anxiety
Patients should be aware of the effect anecdotal reporting can have on their own perceptions about medicines but it’s hard for health professionals to

Comments

Sorry Simon,  this effect has been known for decades, both within Pharmac and outside in the Pharmaco world. That is not to detract from this useful research, but the really useful question would be how much Pharmacos influence, in the background, this genericophobia.

This study proves absolutely nothing about the efficacy or otherwise of  enlafax. Unlike other generics  which have never generated  any serious  controversy, the literature around  bioequivalence for venlafaxine leaves a lot of room for  doubt. Because of the nature of the illness involved, and the fact that increased suicidality was  the  most commonly notified adverse  effect, this issue  should be approached  with extreme caution.